Duloxetine Hydrochloride

Duloxetine HCl (hydrochloride) is a prescription antidepressant, sold under names like Cymbalta and Drizalma Sprinkle, that works as a Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) to treat depression, generalized anxiety, fibromyalgia, diabetic nerve pain, and chronic musculoskeletal pain. It increases brain levels of serotonin and norepinephrine to improve mood and block pain signals, but common side effects include headache, dry mouth, sleepiness, and fatigue, requiring a doctor's prescription and careful use, especially with alcohol or driving.